| Drug |
Temporary
side effects |
Longer
term effects for which children will be monitored* |
| Actinomycin
(intravenous) |
Bone
marrow suppression, hair loss, nausea and vomiting, occasional liver disturbance |
|
| Asparaginase
(subcutaneous; intramuscular) |
Allergic
reaction |
|
| Bleomycin (intravenous)
|
Fever,
hair loss, nausea and tiredness, shortness of breath, sore mouth and skin |
Liver
damage, lung damage |
| Carboplatin
(intravenous) |
Bone
marrow suppression, nausea and vomiting |
|
| Chlorambucil (oral) |
Bone
marrow suppression |
Risk of
reduced fertility |
| Cisplatinum
(intravenous) |
Bone
marrow suppression, nausea and vomiting, damage to kidneys and hearing |
Damage to
kidneys and hearing |
| Cyclophosphamide and
Ifosfamide (intravenous) |
Bone
marrow suppression, hair loss, bladder irritation, nausea and vomiting |
Damage to
kidneys, risk of reduced fertility |
| Cytosine Arabinoside
(Ara-C) (injection) |
Bone
marrow suppression, diarrhoea, hair loss, nausea and vomiting |
|
| Daunorubicin and
Epirubicin (intravenous) |
Bone
marrow suppression, nausea, hair loss, sore mouth |
Weakened
heart muscle |
| Doxorubicin
(Adriamycin) (intravenous) |
Bone
marrow suppression, hair loss, nausea and vomiting |
Weakened
heart muscle |
| Etoposide (VP16)
(intravenous; oral) |
Allergic
reaction, bone marrow suppression, hair loss, nausea and vomiting |
|
| Mercaptopurine (oral) |
Bone
marrow suppression, skin rashes |
|
| Methotrexate
(intravenous; oral; intrathecal) |
Bone
marrow suppression, diarrhoea, mouth ulcers, nausea and vomiting, sensitivity to sunlight |
|
| Prednisolone and
Dexamethasone (oral; intravenous) |
Big
appetite, fat cheeks, risk of infection, raised blood sugar |
|
| Procarbazine (oral) |
Bone
marrow suppression, nausea and vomiting |
|
| Thioguanine (oral) |
Bone
marrow suppression |
|
| Vincristine and
Vinblastine (intravenous) |
Constipation,
hair loss, pain in the jaw, tingling fingers and weak ankles (occasionally) |
|